I'm With Cancer was written by Will Reiser -- who's worked as a producer on Da Ali G Show and Best Week Ever -- about his own struggle to beat cancer. (The movie is about a 25-year-old who is diagnosed.) If you combine an Ali G producer with Rogen and Goldberg, and it's sure to be irreverent, offensive, and completely hilarious. It also will probably be poignant, but not in the on-the-nose, tugging-at-the-heartstrings way that most cancer movies are. (I'm looking at you, Stepmom and Terms of Endearment.)

That's not to say there's anything wrong with schmaltzy sob-fests. After all, if you've lost someone to cancer, you might just want to have a sugar-coated, heroic film version of the disease. But you also might want to be allowed to laugh about it, and that's what Rogen and I'm With Cancer are providing: a reason to laugh about something that's so terrible and scary that we might as well make it funny. [Next Up: AIDS: The Musical! ...What, too soon? - Zach]