Bailey and Cristina's patient is a middle-aged man with some sort of gastrointestinal issues, and he vomits into a pan that Cristina is holding as Bailey asks him about his pain. He explains that he's in the middle of an experiment, and claims that they shouldn't toss the vomit since it could contain important research. Bailey clearly thinks he's nuts as he goes on to say he's working on a cure for asthma. She orders Cristina to empty the pan and come help her but by now Cristina is giving the contents a funny look, and she eventually says she doesn't think Bailey will want her to do that, as she pulls out a wriggling, white, six-inch-long worm. Oh lord, now I'm in danger of barfing and I have no pan handy. Bailey is not amused but her patient, Ivan, just beams at it proudly.

He goes on to explain his research and how he's applying it to asthma, but Cristina can't get over the part where he eats worms. Though he started out only ingesting them for a month or two he went a full year this time so that he could extract more enzymes. As they talk Cristina throws up his x-rays and honestly, it looks like there's some weird, spindly apparatus in his chest, rather than worms. He's proud to see how much the worms have grown, but what it boils down to is that he has a bowel obstruction that needs surgery. He refuses and wants another option, claiming surgery would contaminate his last three years of research. Bailey can't stand the nonsense, but tells him that Cristina will put an NG tube down his nose, which will be extremely painful, and that if that doesn't open the blockage she's then doing the surgery. He's tickled pink at the non-surgical option, however, and when the doctors leave he starts inspecting his x-rays and scribbling notes.

Once out of his room Cristina opines that he is crazy, but Bailey turns the tables on her and points out that crazy is relative, as some people would say missing rounds with Bailey was crazy, but now she's trusting Cristina to take care of her patient. She asks Cristina if she's crazy for trusting and Cristina assures her she isn't, but can't help but point out that she also hasn't been swallowing worms, a very valid point.

As Arizona, Alex and Callie wait for Jake's scans to show up and they talk about his tumor shrinking, Mark pops in to crow that he got reservations for three at the latest, hot, impossible-to-get-in sushi restaurant. Arizona makes a face and claims suddenly to not eat sushi; when Callie calls her on it she claims to have had a bad experience with a prepackaged cafeteria roll. She urges them to go without her and Mark trots off to change the reservation, but he's not dumb and Callie is clearly annoyed. The inevitable bickering is cut off before it can start, though, when Jake's scans show up, giant tumor and all. Callie sighs heavily that she hates her job sometimes.