In Skinner's room, Gail is reading in a chair next to her husband's bed when Celeste walks in. She tells Skinner about the business arrangements she made for him, and mentions that someone named Danny will handle everything else. At his confusion, she explains that Danny will be filling in until he can find someone else. He's confused and calls her name, but she's already out the door. Staring at the cloud of dust she left behind, he asks what's going on, and Gail replies, "Well, I think she just left you." She then gives him her own goodbye and leaves the room. He's still confused, and asks George what's going on. George whispers, "I think I'm done here," and leaves Skinner all alone, with not even his penis fish to keep him company anymore.

In the conference room, Izzie shovels cake into her mouth as Burke walks in. The remains of the cakes are all over the table, and it appears that Izzie has done a lot of the damage. Mouth full, she asks, "Can you be a vault? I think I need a vault because I've eaten, like, a cake and a half and it's just not cutting it. And you don't gossip." He says that's because people don't talk to him, and in reply she spits out that she had sex with a married man. "I don't mind that nobody tells me anything," he quickly adds, but she tells him it was George, and looks close to tears. Like with Callie earlier, I hate the storyline, but I do love the individual characters, or at least I did before it all happened, and she looks so wrecked, it tugs at me a little bit. He grabs a fork and takes his own bite of cake. He muses about what makes the perfect cake, and Izzie observes that he's thought a lot about it. He adds, "This cake, and this day, with this woman." She tells him the red velvet is his winner.

Meredith goes to Derek's trailer and finds him brooding. She says she is apologizing, and kisses him. Again, apologizing for what? For making an effort? I'm getting completely infuriated. He seems mad and tells her she's making light of things, but she continues to give him a play-by-play of what she's doing there. She heads to his bedroom, takes off her clothes, and gets into bed. I think the reason this whole thing makes me so angry and uncomfortable is that I've been there, with the boyfriend ignoring you and making you feel like you did something wrong, and I've done the apologizing for I'm not quite sure what, and it's one of the worst feelings I can imagine. And here it is, in Technicolor on my television screen. He just shakes his head and finally smiles, but still looks sad. Run, Meredith! Remember the sad sex with George!