Jazzy music ushers in another Seattle dawn, and as Mere turns off the alarm and slowly gets out of bed we see Derek already at the hospital, preparing for surgery. Meredith's surprise to see his side of the bed empty clues us in to the fact that he totally snuck out without waking her, and she VOs that doctors practice deception all the time and give vague answers to hard questions. Derek does a scan on his patient and speaks into a small recorder that this is patient No.1of his Alzheimer's clinical trial. Meredith VOs that the placebo has to be the doctor's greatest deception.
Alex tapes a hand-written sign up on the door of the OR before he goes in and OH GHASTLY HORROR NIGHTMARE GAH NO WORDS LAKSJDFOPASIDJF [THUD] it warns that the patient inside is awake. The look on the patient's face is that of controlled fear, though he's trying very hard to be calm and tells Derek he's okay as Derek fires up the drill. Alex then rips open the envelope that contains the medicine and a letter saying that this patient is scheduled to receive... the placebo. It's quite a downer of a start to the study. Meredith watches, pouting, from the gallery as she VOs some more about placebos and how doctors tell themselves that patients who receive them will feel better anyhow, which tends to help when all you're doing is actually leaving them to die. This last line kind of lingers over her scowling face, and it seems a tad disproportionate since it seems to imply that Mere's been left to die when really she was just left to not participate in the trial.
We join Mark and Callie just after she has told him about the pregnancy; he's still in bed but she's fully clothed and just hanging out on top of the covers, which perhaps is too little too late. Mark's shocked but not displeased by the idea and though Callie is flustered and assures him he doesn't have to be involved, he absolutely wants to be. He goes so far as to ask if she wants to get married but she shuts that idea right down, which is good, but the question causes him to remember the small detail of Lexie, which is bad. He drops his face into his hands wondering how on earth he's going to tell her about this and Callie takes the opportunity to run out, not super excited to think about all of that.
She goes across the hall to talk to Arizona, whose puffy face indicates that this maybe wasn't the news she wanted to hear on coming back from Africa to profess her love. Callie gently asks if she's ready to talk; it's now Arizona's turn to be angry and it's kind of a welcome change, though of course what I really hope for is for them to work things out like adults and for their storyline to remain consistent. Arizona admits she wants to yell some mean things while knowing Callie won't run away, so Callie agrees and Arizona goes on a tirade about how angry she is that Callie slept with someone even though it was while they were broken up. She's also angry that person happened to have a penis, even though she knows Callie is bisexual. Callie tries to make a joke but Arizona is so not in the mood -- a surprise ex-sex pregnancy does generally sober the atmosphere. Callie tells her that she didn't plan all this but as now a wee baby is arriving in about seven months, she has to get to planning. She sincerely tells Arizona that she wants her to be a part of that plan. Arizona tells her that she is in, but she also still needs time to be mad. Seems fair to me, and Callie agrees. Thank goodness this looks like it might be the end of Callie playing the victim. I much prefer these two when they are able to get mad at each other like adults, without the fear of actually breaking up a la Coach and Tami Taylor.