Mark finds Derek working away on his research, already a bit beaten down by the emotional punch Alzheimer's can pack. Mark's the man for taking his mind off things, and announces that Callie is having his baby. Mark is over the moon, and insists that he really wants the baby but he's also looking for advice since he doesn't want to lose Lexie over this. Of course, this news isn't exactly what Derek wants to hear since he and Meredith have been trying for months with no success, and he tells Mark he's the poster child for failing up. He's saved from having to come up with any solutions to Mark's problems because Mark gets a page and sprints out of the room.

He runs back to the exam room and arrives at the same time Arizona to see Callie and Lucy in a standoff -- Lucy is sure the baby is okay but Callie still isn't convinced. It turns out Lucy was the one who paged them because Callie hadn't yet left the exam room two hours after the appointment. Callie just starts throwing out various possible complications and doesn't want to take any chances. Lucy is understandably frustrated, even though she's trying to stay nice, and finally Mark jumps in as referee and suggests that since she's there, why don't they just do a culture? Lucy agrees, but seems to be silently judging them to be a pack of lunatics.

Rose watches Daniel and Victoria cuddle and fiddles with her wedding ring as she tells Alex all about how they met in college 40 years before. After watching her husband and his faux-wife for a while she turns to Alex, tears in her eyes, and pleads with him to give Daniel the drug. Alex insists that it's totally random and not up to them but she insists that they could change it if they wanted to. She cries that she can live with sharing her husband with Victoria, but she can't live with losing him all the way. It's completely heartbreaking, and Alex is visibly shaken by the exchange.