George catches up with Izzie, who starts bitching incessantly about George being disloyal and she can't believe him, and as soon as she turns her back, they're best friends, blah blah. Shut up, Izzie. Mere sees them and tries to explain to Izzie that Alex's exam is tomorrow. Izzie: "He CHEATED on me!" Walk walk walk stomp mad shut up please. "He CHEATED on me!" Cristina passes by, all, "I told you she'd find out." Izzie: "Oh, of COURSE you're in on it. He CHEATED on me! With George's skanky syph nurse!" Jesus gay, SOMEBODY turn her off! It would be a Christmas miracle. Mere finally yells, "We KNOW he cheated on you, that's why we let you turn the house into Santa's freaking Village." She goes on to say that they're not big on holidays, but are trying to be supportive, because she's having a hard time -- but right now, Alex is having a harder time. Izzie asks why they even care what time he's having. Mere: "Because he's Dirty Uncle Sal." Ha! Everyone stares, and Mere has to explain that Alex is Dirty Uncle Sal, the one who embarrasses everyone at family reunions and can't be left alone with the teenage girls, but you invite him to the picnic anyway. "I have a mother who doesn't recognize me. As far as family goes, this hospital, you guys, are it. I know you're pissed at Alex, but maybe you could try to help him anyway. Sort of like in the spirit of this holiday you keep shoving down everybody's throats!" Yay! Izzie finally shuts up, and Mere walks off, and I love her.

Scene skipped.

Oh, FINE. It's Nadia's family, and they're all in there yelling that something's wrong with her. And something, uh, kind of is involving her vomiting blood. George runs in and sees that she needs surgery immediately. He yells at a nurse to prep her now, while her family SCREAMS in the background. Loudly.

Mere finally brings an impatient Bailey her shake. She takes big, nausea-fighting gulps as George runs in and says Nadia's ulcer has perforated, and she's vomiting blood by the pint. Bailey asks desperately if the chief is back, and they say no. She tells both of them to scrub in, and downs her shake as fast as she can. Aw.

McDreamy looks at Tim's CT, and sees that he has another bleed, which is probably causing this personality change. He tells Izzie to prep an OR while he talks to Tim's wife. As Izzie walks out, Addison walks in and tries to say hello. Izzie pretends she doesn't exist. Addison: "Nice talking to you!" Heh. Addison tells McDreamy she'll never speak to her again, and McDreamy ignores her as well. Addison says she's feeling strangely invisible today. McDreamy's all, "Huh?" Addison sees he's doing another surgery, and says she guesses dinner and shopping is out. McDreamy says it's not gonna happen tonight; he's sorry. Addison: "No, you're not, I'm just trying to figure out why you're not. It's Christmas, Derek." McDreamy says he knows, and he's fine, and he'll see her at home, and he's totally lying. Addison is, once again, left there standing by herself, wondering why she even tries.