Meredith is finally telling Esme about her condition. Esme looks thoughtful, then says they were supposed to go to Venice at the end of the month. "Do you know the story?" Mere shakes her head no. Esme tells her that the story goes, if you ride a gondola under the Bridge of Sighs, you'll be together for eternity. She then immediately tells Meredith not to tell her husband. See what they did there? Esme doesn't want him to know; he's always so worried about who will go first. Meredith says they can't have a relationship built on a lie. Esme is like, "Oh, you young people. It's not a lie. It's our future. I've been with the love of my life for sixty years, and now I'm dying. We're going to Venice. We're getting in that gondola." You go in that gondola, Esme! Meredith is near tears, and smiles ruefully at the wise old woman.
We switch to a shot of Seattle at night, then to Sav and Weiss and McDreamy and Addison. Sav is telling the McDreamys that they're going to make it, because they were always meant to be. Addison looks hopeful, McDreamy like he wants to slit his wrists. Sav proposes a toast to taking life in your own hands. They all cheer. Then Weiss proposes his own special toast: "And here's to bull, and here's to crap!" HA! "And here's to oopherectomy, hysterectomy, and double bilateral mastectomy. How smart am I to know all those words?" Oh, wait, not so funny anymore. I'd like to note here that everyone stops drinking but McDreamy. My kind of man. Savvy begs Weiss to stop, but he goes on to toast breast reconstruction, nipple reconstruction, losing your wife, and also being the ass who can't be supportive. Hear, hear! Or not. Weiss gets up and leaves, ruining their super-fun time. Commercials.
The next day, Weiss is still dithering about being there for Sav's surgery. McDreamy says they can get through this. Weiss: "This is coming from a guy who packed his bags in the middle of the night and drove three thousand miles to live in a trailer." McDreamy concedes that he might have been crazy to do that, but he's probably crazier now for trying to work things out with Addison. "Am I out of my mind, man? I mean, you tell me." Weiss has no answer for this. McDreamy has some kind of epiphany, and says it's about the ring. He says Savvy didn't screw around with his best friend, and she's looking for support. And if he can't give her that...if doesn't give her that..."then what the hell am I doing?"