Mere starts her voice-over as we fly over Seattle at night. She says that forty years ago, the Beatles asked the world a question: they wanted to know where all the lonely people came from. As we fade into an outside shot of the hospital, then into the NICU, Mere says her theory is that a great many of the lonely people come from hospitals. "More precisely, the surgical wing of hospitals."

In the NICU, George proclaims that his quint, Lucy, is the best one. "She just smiled at me!" Izzie wearily reminds George that she's nine hours old. George insists that of the five babies, Lucy is clearly the best. The rest of Fool and the Gang are parked in front of their own incubators, and Mere says her quint Charlotte is already so smart, she's got wrinkles on her forehead. If that's a sign of intelligence, I must be a freaking genius. Izzie looks over at Mere: "A, this is not a competition. And B? My quint kicks your quints' asses." Cristina points out that Julie has her organs on the outside of her body, and she's still alive, thank you very much. Alex interrupts this amusing scene to boast about his quint, Kate, then try talking to Izzie, who tells him he's way too busy screwing nurses to talk. "Get out." Alex asks if someone will just make sure Kate's vitals remain stable. Mere says she will, which earns her a dirty look from Izzie, who then says, "I am so glad I never slept with him, which is his loss, because I'm really good in bed. Mind-blowing. Mind. Blowingly. Good in bed." Cristina asks if she's trying to seduce them, but Izzie just goes on freaking about how she can't believe he slept with Olivia instead of her. George is like, "Hey. I slept with Olivia." Izzie: "Well, then you both have bad taste." Damn. George doesn't know why she's even surprised; she knows how Alex is. Mere tells Izzie she dodged a bullet, and is better off without him. Cristina wonders why she's even surprised, since if you sleep with a snake, you get bit. Izzie thanks them for their "support." Bailey walks in and asks who's on call; Izzie says she is. Bailey tells the rest of them to go home and get some sleep -- all five quints are still alive, so it's been a good day. Mere takes this opportunity to finish her VO: "As surgeons, we ignore our own needs so we can meet our patients' needs. We ignore our friends and families so we can save other people's friends and families. Which means that, at the end of the day, all we really have is ourselves." Over shots of each Fool sleeping or sitting sadly alone, Mere says, "And nothing in this world can make you feel more alone than that."