Lexie and Derek are in surgery and Mere was right -- he's totally engaged in the work and so not yelling at Lex. He's gotten it out of one side of the brain but vessels are covering the other side and making it hard to get to. Even though Lexie's not a fifth year she rolls over and gives up like one, telling Derek that at least Mary has six months, and they did all they could. Derek realizes what she's saying and says with almost a laugh in his voice that they aren't stopping. The tumor may be smart, but they are smarter. Uplifting music seems to say that this crazy plan might just work.
Cristina finds Callie in the scrub room after Tyler's surgery and immediately starts to try and rationalize her cowardice by reminding Callie that she'll have to defend every decision she makes in surgery in her boards. Callie's unimpressed and just tells Cristina that she picked her to be co-surgeon because Cristina takes crazy risks. This week she just played it safe and boring, and while Callie knows how competitive and scary this year is she warns Cristina to be careful not to lose herself. As happens so often among the Seattle Grace surgeons, though, she keeps talking and suddenly she's talking about her own life and griping about people who like to talk about food as if it's an orgasm. A confused Cristina snaps her out of it and Callie just orders Cristina not to let fifth year get to her. Cristina just heaves a sigh as if she's not sure how to prevent that, but that's so ridiculously far out of character for her that I firmly believe she can kick her own ass somehow back into being awesome.
Meredith sees Clay waiting with Emma and asks to sit with him, which he happily accepts. Emma is doing a great job keeping up the tradition of ridiculously cute Grey's Anatomy babies with her little button nose. We then get the Serious Surgical Montage, that shows them waiting as things start to get tense in the OR. A vessel started to leak and Derek has to drain the tumor, so he asks for a needle. Lexie is shocked to see that he's going in blind but Derek tells her he doesn't have a choice. This show is full of cliched, overdramatic medical moments but usually I still get kind of sucked in; unfortunately something about Lexie's exclamation and Derek's tough but take-charge answer just made me laugh this time.