She then VO's: "Practicing medicine doesn't lend itself well to the making of friends." Izzie takes off her badge as Bailey, Alex and then Richard watch her from the doorway. Alex drops his head -- it's clear that his heart is totally broken to bits. "Maybe because life and mortality are in our faces all the time. Maybe because in staring down death every day, we're forced to know that life, every minute, is borrowed time."
While we don't hear what she says, we see Bailey tell George the news and he turns and starts to run towards his friend as she drops her head in anguish. Back at the trailer, Derek sits with his head in his hands. After a moment, though, he picks up the scans as Meredith goes on: "And each person we let ourselves care about is just one more loss somewhere down the line.
"For this reason, I know some doctors who just don't bother making friends at all. But the rest of us? We make it our job to move the line. To push each loss as far away as we can." Back at the hospital, Meredith ties Izzie's hospital gown while Alex puts on her bracelet and Cristina listens to her heart and gives a small smile. George runs in and he and Izzie have a Best Friends Moment before he smiles at her through his own tears. She gets into bed with the help of her friends and Cristina takes her wrist ostensibly to take her pulse, though it looks like it's her own way of once again giving Izzie a friendly touch. Izzie then sits forward and starts to talk as the others gather around. And while I seriously thought I was numb to any story involving Izzie Stevens, I just added the last bit to the tissue sculpture that's going on my coffee table, because that was seriously some well done heartstring-tugging right there.