We open in Joe's bar, where the TV is tuned to a basketball game. Meredith blah-blahs some voice-over stuff about basketball and the game of life, but I cannot possibly pay attention to that because we then pan over to Meredith, sitting on a barstool, doing some of the ugliest knitting I've ever seen in my life. Joe leans over to McDreamy, sitting behind her, and asks, "Is she knitting?" A good question, Joe. She says that she is, but it appears that she...is not. McDreamy slides over and tells her she looks a little weird. Joe claims she can't knit in a bar, and they urge her to have a drink. Mere, still furiously "knitting," says she can't have a drink; she's celibate. Drinking leads to celibacy, you see, and knitting is good for the celibate, so she's making a sweater. Oh, the poor sheep that gave their wool to this crafty abomination are going to be so sad. Mere says again that she's having no more men, and Addison scoots up next to her, all, "No more men? YOU?" Heh. She continues that every guy she meets turns out to be married, or Mark, or...George. McDreamy: "You're making a sweater." MereVO tells us that we play games to make life more interesting, or sometimes, to distract us from what's really going on, and from here we cut to...

…Izzie, lamenting to a recuperating Denny how Meredith broke George and ruined his life. Izzie is also knitting, but she's clearly totally awesome at it. Denny looks at her with interest as she segues into slamming Callie -- "What kind of name is that, anyway?" -- and then puts down a triple word score on the Scrabble board in front of them. Denny is not only feeling much better, he's horny as hell: "Sixty-nine points. I'm beating the pants off you! Pay attention!" Izzie says she's knitting a sweater; actually, she's knitting part of one for Meredith, because they took a celibacy vow, and she's replacing sex with knitting, because she broke George. Denny's head snaps around at this. "You took a vow of celibacy?" Izzie answers in the affirmative. Denny would like to know, please, how he's supposed to get in her pants now? Izzie sasses that that is a very inappropriate thing to say to your doctor. Denny says that she promised if he lived through this they'd have sex...in his head. Izzie pretends to be offended, but she's eating it up. Denny, sadly: "Don't worry. You weren't very good." Hee. Izzie says she was being nice and letting him win at Scrabble because he's all sick Mister Needs-A-New-Organ Guy, but now she's going to kick his ass. She glances at the board. "You put down 'mount'?" MereVO: "There are those of us who love to play games. Any game. And there are those of us who love to play a little too much." We cut to Cristina and Burke's, where they're in a heated game of Celebrity (Confidential to Sars: "LET'S PLAY CELEBRITY!" ["Quiet down!" -- Sars]) against Callie and George. George calls out "Disastrous FEMA director" to Callie. She takes it down to the buzzer and yells, "Michael Brown!" Cristina has some crazy competitive Manson Lamps going on. She pushes the clock and yells, "Time! TIME! TIME!!!!" George and Callie gloat while Cristina sulks and opens her clue ahead of time. They call her on it, and she's all, "It's called strategy." Heh. Burke says it's just a game, and she seems a little intense. Cristina says she's having fun, and she's ready. She makes a total "we got it" face, and hits Burke with the clue: "Blonde Ambition Tour." Burke has no idea. Cristina can't believe it. She jumps up and starts freaking out. "Blonde Ambition Tour! Vogue! She's blonde! And ambitious! With the...with the...cones! Boob cones! Vogueing!" Haaaaaa. Time runs out, and they don't get it. Poor Burke's all, "Oh, Madonna, riiiiight." Cristina is livid.