We head back to the House of Shame, where Meredith is listening to her door to make sure George isn't walking down the hallway so that she can avoid an awkward moment. She opens the door and…there's George, walking to the stairs. Hello, awkward moment. Luckily, Mere and George don't have to talk to each other, because Alex busts out of Izzie's room with his pants around his ankles and makes tracks for the bathroom. Mere and George look at each other with embarrassment oozing out of every pore. Izzie steps out of her bathroom and greets each of them in turn and her sex hair is HIGH-larious. It looks like she dressed up in a period costume with matching wig, filmed a scene where she was rolling around on the moors with Heathcliff, then retired to her trailer, boinked her boyfriend without removing her costume or wig, and fell asleep. Then she woke up, bent over at the waist, grabbed some AquaNet and sprayed the shit out of her hair, changed into pajamas, and…walked out of her bedroom to greet Mere and George. This sex hair is awesome. This sex hair is so awesome, it needs its own damn trailer.

So, Mere and George are standing there, all embarrassed and silent, and Izzie mistakes this for judgmental silence on their part. "What?" she says in a snotty tone. "So I slept with him again. So I'm a big whore. A big horny whore who can't get enough. Can we get over the shocked silence already?" Mere and George just look at each other as George says something about karma and how, any way you slice it, karma sucks. And thus, we have tonight's theme.

Medicine Crüe Locker Room. Everyone's getting ready for the day. George goes to wash his hands, but Meredith's at the sinks, so he turns and skitters off like the four-year-old he is. Alex, Izzie, and Cristina are observing Mere and George and their odd behavior and they're speculating as to what's going on. Alex thinks George caught Mere doing McSteamy. Or maybe McDreamy. "Did I just call that dude 'McDreamy'?" asks Alex. "Oh, you know you did," sasses Cristina. Heh. Alex snuggles up to Izzie in plain view of the whole locker room and tells her she is ruining his life. She's like, uh huh, yeah, go play with yourself. Izzie's totally using Alex for sex and he has NO clue. Love it.