George sees Callie and walks up to her. She tells him that they need to talk. He's clearly prepared to tear into her over the Mark sex, but she tells him she needs to talk with him about his dad. And then a nurse opens the curtain around a patient and we see George's dad in a hospital bed. Mere V.O.: "And then there are the wounds that take us by surprise."
Joe's bar. Mark is sitting at a table with Meredith. He tells her, "This could be just a drink. Or this could be more than a drink." Why is she drinking with him? He's so obviously not a nice person. And why is he compelled to chase every woman in McDreamy's life? She tells him that she can't start something with him. He tells her, "Start over, Meredith. Start fresh." Honey, I would not call what you're selling "fresh." Mark's pager goes off. He leaves to...find a phone, I guess, although I can't imagine he doesn't have a cell. But maybe it's too loud to make a call from in the bar. He asks her to order him another beer.
Meredith walks up to the bar when Derek walks into the joint. He walks up to her and says, "Hi. I'm Derek Shepherd." And he holds his hand out for her to shake. She asks him what he's doing. He tells her that he wants to start over with her, at the bar where they first met, but taking time to actually get to know each other. He introduces himself again, and she tells him, "You walked away. And now it's too late. There's too much water under the thing, or whatever." Derek: "Meredith. Please." Mere V.O.: "The trick with any kind of wound or disease is to dig down and find the real source of the injury." McSteamy walks back into the bar and Meredith sees him over Derek's shoulder. Derek smiles at her, and she holds out her hand and says, "Hi. I'm Meredith Grey." Mere V.O.: "And once you've found it, try like hell to heal that sucker." Meredith and McDreamy kiss. And kiss some more. Credits.