George is eating a sandwich and looks up to find the three Furies looming over him. We establish that John Doe's liver is an excellent match for Lloyd, and that Lloyd is the Chief's good friend. Cristina dangles the prospect of George being involved in the transplant surgery, and he tells her that he doesn't need to be manipulated: "If you want something, all you have to do is ask." Izzie: "We want you to go over Burke's head to the Chief." George: "Ask me something easier."
George, of course, gave in. We see him waiting to ambush the Chief as he emerges from an OR. George, stammering and stuttering, explains that the interns have located a liver for Lloyd. Cut to the three Furies, watching from the side. They think Burke will condemn them straight to hell for going over his head. An extra walks through the scene carrying some sheets, and he does a complicated little piece of business with his glasses. That's some dedication to the craft of acting, right there. Alex comes upon our three heroines and asks them what they're up to. In unison, they tell him, "Nothing." Over their shoulders, we see Burke walk by George and the Chief. The Chief grabs him and explains about the donor. Burke gives George a withering glance, and George turns on his heel and walks away. Izzie laughs aloud, and Burke turns and sees the interns. All three women turn and run, while Alex looks stupid. Burke walks away, but Alex realizes something is going on and chases after Burke, calling out his name.
Gah! Beating heart! Burke is performing the surgery needed to keep John Doe's body alive. Alex kisses his ass. The camera pans up to the gallery, where Mere, George, Cristina, and Izzie are watching. Meredith calls Alex "vermin," noting that the surgery belonged to one of them. Izzie is just happy the surgery is happening at all. Izzie thanks George for his help, and he explains that he now fears that Burke will kill him and make it look like an accident. A nurse enters to tell them that John Doe has been identified; his wife is on the way. Wait, there's a Mrs. John Doe? Well, there go Izzie's chances.
Izzie sits with John Doe in post-op. McDreamy opens the door to the room for Mrs. Doe. She is appropriately emotional. McDreamy introduces her to Izzie and then tells her to call if she has any questions. Mrs. Doe asks Izzie if there's still a chance for John to recover. Izzie tells her that they can hold off until the morning, but that if there's no change they'd like to discuss organ donation.