Derek is still at Mere's house -- when he can't find her, he sits down on her bed and puts his head in his hands.
Lexie's back at her apartment examining an orange when George bursts in and tells her he's retaking his test. She's thrilled for him and he goes on to say that he knows he was mad, but thank you thank you thank you! He then grabs her and plants a kiss on her lips. As he runs off looking for alcohol for a party, she touches her lips -- with that, George O'Malley has snared yet another woman to make him officially second only to Mark in the race for Seattle Grace Ladies' Man.
Alex is sitting on his bed, looking like a broken man with tears in his eyes, when Izzie comes to the doorway. Maybe the door was unlocked because they were home, then? But then why wouldn't one of them just tell Derek that Mere was out and shoo him out of the house? Oh, who knows, it's the last five minutes of the season, so I'll just let that be. Izzie leans in the doorway and tells Alex she's sorry, and he tonelessly just shoots back, "Whatever." She walks in and sits down next to him, saying, "Not whatever. I'm sorry." She's sorry for what happened with Ava and his mom. That seems to have gotten him, and he turns to her, an absolute mess, and grabs her face and kisses her. She pulls away but he begs -- it's horrible and desperate and really raw -- "Just this once. Just for one night. Please." She gives in and they make out, while elsewhere both Richard and Adele and Callie and Hahn do the same. Izzie pulls away again and Alex's face is a red mess of tears as he begins to sob and beg again. She pulls his head to her chest and just holds him. And I pull out some more Kleenex.
Bailey gets to kiss someone too... except, of course, we never get to see her be romantic at all, and her kiss is with her exceptionally adorable son. But she's happy, and she tells him they're going home. "Home to daddy." So maybe there is hope after all!