Back with Megan, her monitors are beeping wildly and there is a flurry of activity over her. Cuddy tells House that his little Tamoxifen stunt has just about killed Megan. "That doesn't mean I was wrong!" is all House says before the commercial.
As there are no janitors around to bounce ideas off of, House limps down to the ER, where a group of med students are getting their hands dirty. He makes a general announcement to the room asking for a doctor to help him with a differential diagnosis, and he's soundly ignored. "Am I in an M. Night Shyamalan movie?" House wonders. I hope not, because then this show would suck. One bright spot: Wilson would be played by Joaquin Phoenix. One spunky young lady tells House that Cuddy issued a memo to the entire hospital telling them to ignore House and not enable him. Megan thanks you for her death sentence, Cuddy.
House gives up and leaves, but he's followed out by that spunky young lady, who impresses House by deserting her patient, a meth-head who shot herself in the leg, to be his bitch. House guesses she's angling for a job with him, but she says she just "cares about people." Unless they're meth addicts with leg wounds. Shouldn't this spunky young lady be wearing a vest? Perhaps not, as House dismisses her diagnoses and then says her caring about people makes her ineligible for a job with him. Good to see he's learned from some past hiring mistakes. Spunky young lady immediately says she was lying and hates people for real. She puts out a few more theories, and House responds by telling her that her eyes are lopsided. "And by eyes, I mean breasts," he adds. Spunky young lady can't help but glance down at her apparently nonsymmetrical chest. House asks her why she won't guess that Megan has both Crush Syndrome and Acute Respiratory Distress Syndrome, to which she replies "because then there's nothing we could do." "Boy, you remind me of someone," House says. "Send me your résumé."
House returns to Megan's room, where he finds Ben, who says he couldn't leave Megan after all. "I love her," he says. Somewhere, a Cameron is singing. House asks Ben how he can love Megan when he didn't even really know her. I think he answered his own question. Sally Field comes to Ben's defense and asks House why he's antagonizing Ben. But House isn't done yet: he tells Ben that not only was Megan a completely different person than the woman he thought he fell in love with, but she's also got Crush Syndrome and Acute Respiratory Syndrome and is dying soon. Oh, but wait...what's this? House spots a lump on Megan's arm. He says there might be hope for her after all, and goes off to get a biopsy.