It's already in progress by the time he arrives, and Kumar's passing the time by chatting with Sophia about local foster homes. He says most foster parents are good, well-meaning people. Well, Sophia's already got her GED and emancipation papers, so that ship has sailed, Kumar. Stop trying to sell her on the foster parents. Foreman's not seeing any spasms on the fMRI monitor, but Kumar sees something odd and asks Sophia how she found out that her parents were dead. Sophia says a state trooper came to her door, and Kumar presses on, asking her for more details. Foreman notices whatever's caught Kumar's eye now, and they both exit the booth to talk to Sophia. Kumar explains that the fMRI showed that she was using the limbic region of her brain when she was answering his questions -- and that's the region of the brain that houses the imagination. Which means that Sophia was lying. Well, well, well -- it would appear that it's the fMRI that's the polar opposite of the MRI (of DOOOM!!) and not the CT scan after all. The fMRI is good and honest and true, and it'll sell your ass out if you aren't the same. The MRI (of DOOOM!!) just makes your ass bleed. Kumar is pissed, saying he put his job for her because he trusted her. I guess he's learned his lesson about that now. Sophia says that she wasn't lying about doing drugs, and only claimed that her parents were dead because the truth is that her dad raped her and her mom refused to believe her. Well, that's a conversation-ender.
Back from break, Kumar tells the meeting room that the fMRI was negative for Foreman's diagnosis but positive for the fact that Sophia is a liar. It also means that Kumar is no longer personally involved in the patient. He was only using her for her orphan-ness. Now that Sophia's problem is more unique to women, the personal connection shifts to Hadley. It always does eventually. House gets right down to business, and Hadley gets all bent out of shape that he didn't stop to observe a moment of silence for Sophia's rough childhood first. Taub suggests that Sophia got an STD from her dad. Kumar suggests that Sophia is lying about the rape, too. Hadley loves Sophia now, and defends her lying by saying it's better to have dead parents than rapist parents. "You find that unsympathetic?" she demands. What's her problem? Kumar put a lot on the line for Sophia, and she lied to him and he feels like a chump. House says Sophia's life is a mess, and asks what rhymes with that. Um ... chess? Did she play too much chess? Can you get sick from that? Oh, no -- it's stress. House says severe stress could cause Sophia's symptoms, because the human brain is so freaking amazing/evil that it mental problems can have physical manifestations. Hadley says that in this case, if House is wrong the treatment is just some simple anti-anxiety meds, so they might as well give it a whirl. House orders Hadley to shoot Sophia up with diazepam (Valium? That's a simple anti-anxiety med?) and Foreman to watch her. And Hadley to watch that Foreman is watching her. But ... if she's watching Foreman, how can she see to shoot Sophia up? He'll have to, like, sit on Sophia's lap or something so Hadley can watch them both at the same time.