Wilson finds Cuddy crying in her office. Wilson instantly knows that it's House-related, and asks her what happened. She says that she's seen House be mean to people before, but that it was always to achieve something. This time, he was mean to her just to be mean. Wilson wonders what House could have possibly said to Cuddy to make her this upset. She says that House actually has the ability to be tactful and hold himself back from really hurting people. This time, he didn't hold back and said the one thing he knew would do this to her. She tells Wilson how she'd been trying to get pregnant, and that House called her a failure as a mother. And House knows that Cuddy knows he's right. She failed to conceive (I'm sorry she's upset about this, really, because I don't want to see my Cuddy upset. But I'm also really happy we won't have to deal with the Cuddy-is-a-new-mom story arc, especially after suffering through this story arc. No more story arcs, show), and she failed to be a mother to Alice. Instead of being natural and caring, Cuddy felt awkward and terrified and even told Alice that her parents might get back together just to make the kid feel better. Wilson's like, "Uh...yeah...maybe that was kind of ill-advised." Cuddy wonders if she just doesn't have a natural maternal instinct. Wilson says that House certainly did poke the right spot. DUH, Wilson. Now what are you going to do about it?
Alice's rash is spreading. It's all over her left arm and leg. The Rocky Mountain Spotted Fever medication isn't working.
House is still in pain. The Cottages are still sulking -- especially Chase, who's sure they'll find a way to blame this on him screwing something up like they always do. Well, it's about freaking time he stood up for himself! Too bad it he waited until he pretty much had nothing to lose. Oh well. House says that the infection must have moved into Alice's muscle sheath -- necrotizing fasciitis, a quick internet search for which pulled up a whole bunch of bad, bad images. The only thing they can do for Alice now is to amputate both her arm and leg before the infection spreads. Cameron doesn't want to do this without a confirmed diagnosis, because she apparently just got amnesia and forgot the last three years, every day of which her boss had absolutely no problem taking drastic action without a confirmed diagnosis. House says that they don't have time for confirmation. The Cottages continue to disagree, so House screams at them. He says he knows their patient is a cute little six-year-old, but that they're not going to cure flesh-eating bacteria with sunshine and puppies: "Cute kids die of terrible illnesses! Innocent doctors go to jail! It's because cowards like you won't stand up and do what's required. You can sit around and moan about who's the bigger weakling; I'm gonna go do my job." You guys, I don't think he's talking about Alice here. I don't think he's talking about himself either, because last time I checked, he wasn't innocent. And if he really thinks he is, that's all the more reason for someone to put him in check. I just don't think this was the way to do it.