House continues his trash analogy and tells the Cottages to check the brain's "trash," by which Foreman figures out he means the blood-brain barrier. Again, House is kind of surprised that Foreman knows what he's alluding to so quickly. He orders them to biopsy the barrier. Foreman also thinks that they should treat Harpo for worms, infections, and STDs, just in case that's what he's got. House scoffs at the last suggestion, saying he doubts that Harpo is cheating on his gorgeous wife and that he doesn't think she cheated on him either. The Cottages look surprised -- not because their boss has, for what must be the first time, taken a patient's family member at her word, but because Harpo is a widower. HIS WIFE IS DEAD! And then House looks down at the car and sees a bloody hook dangling from the door handle! And the call is COMING FROM INSIDE THE HOUSE! And then Cameron removes the green ribbon around her neck and her head FALLS OFF!