The Branfam plan his upcoming nuptials. Brandon wants his cousin Sharon to be there. Mom says that if they invite Cousin Sharon, they'll have to invite "all the cousins." "So what?" says Mindy. "My side of the family doesn't eat anything." Everyone laughs as Mom silently plots how to kill this horrible girl her son is trying to bring into her life. She may have forgiven Mindy for accusing her of almost killing Brandon, but Mom draws the line at vague fat jokes. Brandon coughs and asks if he's allowed to have cough medicine now. Cameron and Chase say that's fine. Chase tells Brandon to invite House to the wedding. He won't come, but he'll send a gift. And Cameron will "make sure" it's a good one. What a nice planet Cameron lives on, where wearing extremely low-cut V-necks with her boobs almost hanging out is acceptable professional wear, and where she and House hang out at the mall and shop for people's weddings together. Brandon notes that these new cough medicine pills are different than his other ones. The new ones have a letter on them; the old ones didn't. Cameron tells Brandon not to worry about it, and then turns down Chase's date proposal before he's even finished making it.
"One is the loneliest number that you'll ever do," Three Dog Night sings as House, still searching through the pharmacy, finds a bottle of small, yellow pills without a letter on them. He compares them to the right pills and looks up to the sky. "Thank you, God, for making me so damn smart," he thinks. Or he would, if wasn't so pissed at God for making him a cripple. Two can be as bad as one, but not when it comes to legs, eh, House?