Frankie is being prepared for her surgery. Taylor is with her, although whether or not he'll be around when she wakes up is not known. Frankie says she hates that Taylor doesn't have a blog, because she has no way of knowing what he's thinking. Um, what? Really? I'm pretty sure humans were able to convey their thoughts to each other in the thousands of years our race had before the advent of blogs. Suddenly, Frankie has a sharp pain in her right side. She screams and barfs yellow fluid.

Frankie had her surgery, but instead of replacing her mitral valve, they removed her burst appendix. Wow, it burst just like that? With no pain beforehand? They took a biopsy of the appendix and found that it was full of "abnormal cells," most likely lymphoma. So now Frankie has cancer! And it's so far advanced, especially now that the appendix burst flooded her entire body with cancer cells, that they don't think there's any point giving her chemo. Foreman says they still have one chance to save her, though -- Cuddy approved an experimental treatment in which they use Frankie's unique cells to create a lymphoma vaccine. Way to make it happen off-camera, Cuddy, thus giving Lisa Edelstein the week off! Frankie asks if that will save her life. Chase says they're not exactly sure what it will do. Hopefully, it'll train Frankie's immune system to fight malignant cancer cells. If she doesn't do anything at all, they give her "maybe a year" to live. That's kind of a long time, actually, as far as cancer so advanced it can't be treated with chemotherapy is concerned. Are they sure they can't do chemo? Taylor urges Frankie to do it, saying he'll be there for her every step of the way. Frankie says the vaccine sounds fine and to start as soon as possible.

In the hall, Foreman takes off while Chase stays behind to speak to Wilson's assistant, Sandy. "Can I borrow your car?" he asks her. Some time later, he's working on the cancer vaccine with Hadley and amazed that Sandy just gave him her car keys. He thinks his good looks have struck again, and frets about how all this time, he thought he was connecting with people when they were really just pretending to care about what he was saying because he's hot. Hadley decides to tell us all a story from her own life, saying the first man she fell in love with was a great guy until she realized that he was acting the way he thought she'd like just to be with her because she's hot. Also, he was 30 and she was 17. Hmm. Someone's got Daddy Issues. From this, Hadley says that it takes time to really get to know someone beyond his or her physical appearance, but it's the stuff beyond the physical that makes a relationship really last. At least, I think that's what she meant. I don't really know. This stuff is all common sense and we all learned it by like third grade. I just don't understand why it's all news to Chase.