House plays Battleship with Wilson. He's very good. And it involves taking shots. Also, they're using pizza boxes instead of playing actual Battleship. House takes the opportunity to interrogate Wilson about why he freaked out about the proposed treatment plan. He should be in radiation right now! Wilson walks off.

Adams and Taub monitor the MRI. From inside, Emily admits that she was only pretending to be asleep while the Lawsons argued. Taub says that his daughters do that sometimes too and Emily asks if his wife ever wants a divorce. He's not very convincing as he claims that everything's fine at home. "Hold still now! No more talking!" Adams wants to talk about Dr. Lawson's tendency to call Emily "The patient." Just then! Emily starts crying out in pain! And she won't say where it hurts! She just wants her daddy!

House's office. Taub says they were able to return circulation to Emily's hands and feet. Adams speculates that it was stress. Dr. Lawson shuts that down since Emily's heard the Lawsons fight a lot. She also rejects lupus. And she's shown no signs of immune activation. She suddenly decides that it could be heavy metal poisoning because Simon just moved into a new place and hey, maybe it has lead paint or something. Chase says that lupus is a better fit. Dr. Lawson says, "I don't mean to pull rank here, but I am her mother." Chase says she was supposed to be here as a doctor. But she claims that parental consent is needed for any treatment, so she gets final say on everything. She leaves to go do tests on pain and orders the team to start on whatever it is you do for heavy metal poisoning. When she's gone, Chase says they should treat her like any other mother.

So naturally, the next scene is Chase nosing around Dr. Lawson's place. He calls it "the environmental mother lode" because it's full of medical stuff. Adams is there with him and she doesn't think Emily would get to come down to the medical basement. Well, there's a playpen right there. They find some Lex-2, which is an experimental antibiotic that can overrule DNA. Adams isn't convinced it's being used on Emily, but who else would be appropriate?

House walks into Wilson's office, ignoring Wilson's claim that he has a headache. House has researched Wilson's activities and he's learned that Wilson has had five opinions already. Wilson wants a chemo dose so high there's a one-in-three chance it'll kill him. And why didn't he tell House? Because he knew House would interfere. But that means he's already found someone to prescribe it. And House knows who would do that: Wilson himself! There's a bag of chemicals right here! Wilson admits that he's been stockpiling equipment at his apartment. House wants to attack the bag with a knife, but Wilson thinks he might as well just do the extreme treatment right away. He's got a series of stories about people who died of cancer when they had good survival chances. "I promised him he'd be fine. Eight years old. I am not going to die slowly in a hospital bed under fluorescent lighting with people stopping by to gawk and lie about how I look. Even a small chance of that happening is too big a chance for me." House puts away his knife and calls Wilson an idiot who's probably going to die. On his way out of the office, he says to do it at his place.