Chase tells Dr. Lawson that they think the environmental factor was her own drug. Foreman dismisses her claim that she tested it on herself. She says that Emily wouldn't have survived the winter without it. You can't test something on yourself! Foreman tells her that he's talked to the people who are officially testing Lex-2, and it's linked to renal failure in rats. Chase goes off to see if it's reversible.

House's place. Unauthorized treatment. House pours himself and Wilson martinis. "To stupidity. To muscle aches. Spasms." And on and on. I'm sure Wilson knows all the unpleasantness that comes with chemo. Wilson's on my side on this, pointing out that he's an oncologist. House describes everything in horrific detail and ends with, "Now. What are we doing here, Wilson?" Wilson gives him a bag of chemicals.

Chase uses what I think is an ultrasound to look at Emily's kidneys. He lets her use it, but then BEEP BEEP BEEP! Emily's chest hurts. Chase: "It's definitely not her kidneys."

House gives Wilson some soup and promises it'll taste as good coming up as coming down. Wilson has a bandage around his arm. Wilson starts to tell House something and I suppose I have to transcribe House's response: "If you're going to say that you've always been secretly gay for me, everyone always just kind of assumed it." Very droll. Wilson appreciates the risk House is taking, since if Wilson dies in House's apartment, it wouldn't look good to his parole officer. They chat about where House should dump Wilson's body. Then Wilson's hand twitches a little, which lets House diagnose the muscle twitches that normally come only after the second bag of chemicals.

Wilson is wrapped in a blanket and doesn't look good at all. He tells House that he always thought he'd get sick with a wife and kids taking care of him. House asks if he was in this fantasy. "You have everything you need right here." Specifically, an extremely powerful painkiller. House injects himself too. Wilson: "Oh! That is nice."