Back from break, House shows off his own sleight-of-hand abilities, making a playing card disappear and reappear in his hand while telling the Numbers that Flynn must actually sick with a nose bleed like that. Kumar is pleased as punch, because he's an asshole. Now that they have a real case, House ends the Cuddy Thong Challenge, at which point Cole produces a bright red thong and tosses it on the table. Sorry, Cole -- the contest is over. You shouldn't have waited so long for the dramatic reveal. Without any prompting, CTB stands up and shows everyone the band of her thong, indicating that since she's wearing it, the red one can't be hers. Unless, of course, she just brought an extra pair into work that day. Why are we operating under the assumption that women only own one pair of panties, and that each matches one bra? Am I the only loser with multiple pairs? Thirteen does not share CTB's eagerness to show off her bloomers, even though she'd be the most likely suspect, since she and Cole were kind of friends, weren't they? Except now Kumar is Cole's friend. I guess Thirteen just doesn't have any more room in her life for friends, what with all her MYSTERIES. Anyway, House doesn't believe the panties are really Cuddy's, nor did he bother to come up with a way to prove it before thinking of this challenge. Sorry, Cole!
Back to Flynn, Thirteen runs down his history, which is pretty much free of heart problems. CTB guesses something with a lot of letters in it, and PS suggests cocaine, even throwing in the lingo with a line about Flynn taking "regular rolls in the snow." Aren't you cool, PS? House sends PS and Kumar to Flynn's house to look for cocaine, and CTB and Cole to test for CTB's diagnosis of a bunch of letters. As for Thirteen: she gets to have her own subplot and is called into House's office.