In an interview, Lindsay says that they don't know anything about Lyme Disease, and they need to learn more about "the psychological effects." Oh, now they're suddenly concerned, when it's too late to help Irene in any way. The remaining roommates meet with Karen, the Chairwoman for the Lyme Disease Foundation. I think this episode might qualify for most uses of Hip, Squiggly Font ever. In an interview, Stephen says that Karen has Lyme Disease herself. Karen explains that most people don't know that they have the disease, and that she got it while she was pregnant. In an interview, Lindsay PSAs that there is not much known about Lyme Disease, and that not many people take it seriously. David asks whether you can die from it. Karen says that you can. David wonders whether the disease will eventually catch up with Irene. Karen explains that it affects different parts of the brain, and that it can cause confusion, the inability to understand conversations, and loss of part of the ability to think or function. Okay, David had some decent questions, but now Stephen asks the dumbest question ever: "Does it bring out the worst in you? Is that what it is? Like, bad things about you, or something?" Yeah, Lyme Disease targets your personality flaws, Mr. Academian. Karen explains that it does cause uncharacteristic behavior. Lindsay and her breast implants explain that it was confusing, because Irene would alternately blame her Lyme Disease for her behavior, and then claim that the disease had nothing to do with the way she was acting. Janet explains that Irene's thoughts weren't focused, even though you could tell that her mind was always going. Nathan brings up the stuttering. All of the roommates start talking at once, and this is clearly more group therapy than anything else. Karen tells them that they'll never sort it all out, but that often people with the disease say things they wish they could take back. In an interview, Stephen says that Irene is a strong person who doesn't want to seem weak in any way, so that's why she refuses to blame her disease. Karen explains that a stable environment is the best place for Irene right now. I love that the producers just wrap this all up with a bow -- she was crazy with the Lyme Disease -- when I think it's much more complex than that. But on to the next story line, right? That Afterschool Special is over.