Man, Christina Applegate has been dealt a load of you-know-what in her thirty-six years. She spent the first part of her career establishing herself as a dumb ho in Married With Children and Don't Tell Mom The Babysitter's Dead, and the rest of it up to now trying to prove that she is the polar opposite. Add to that a not-so-fun divorce from Blue Steel-lookin' hubby Johnathon Schaech and a plagued Broadway debut (she took that whole break a leg thing sort of literally). But things were starting to look up! She killed in Anchorman as an able comedic sparring partner with Will Ferrell, and even had some success with a new ABC sitcom Samantha Who? (Full disclosure -- I kind of love that show.) So when the poor darlin' announced she had boob cancer, my heart went out to her.